Depression is a serious and common medical illness that negatively affects how you feel, the way you think, and how you act. It can lead to a variety of emotional and physical problems and can decrease a person’s ability to function. While many treatments are available, some individuals do not find relief through traditional methods. Here’s information on treatment-resistant depression and how SPRAVATO treatments may help:
The Basics of SPRAVATO
SPRAVATO is a prescription nasal spray that contains the active ingredient esketamine, a compound related to ketamine. This treatment works differently from many oral antidepressants. SPRAVATO works on the N-methyl-D-aspartate (NMDA) receptor in the brain.
By targeting this pathway, it is thought to help restore certain neural connections in the brain that are impacted by depression. This process is distinct from that of many conventional antidepressants, which primarily focus on neurotransmitters like:
- Dopamine
- Norepinephrine
- Serotonin
SPRAVATO is a self-administered nasal spray, provided in a doctor’s office or clinic where patients are closely monitored by a professional for at least two hours following each treatment. Your provider determines the specific treatment schedule for SPRAVATO and tailors it to your needs.
The Uses of SPRAVATO
This esketamine treatment is specifically recommended for adults with treatment-resistant depression (TRD). TRD is a term used to describe cases of major depressive disorder (MDD) that do not respond adequately to at least two different oral antidepressant treatments taken at a sufficient dose for a significant duration. For individuals living with TRD, the persistent symptoms of depression can be particularly challenging, making daily life difficult.
SPRAVATO offers a different approach for these individuals who have not found relief with other therapies. TRD typically has similar symptoms of MDD, including impacts on appetite, mood, and sleep. Because of the resistant nature of TRD, those with it may experience more symptoms, like:
- Longer, More Severe Depressive Episodes
- Greater Amounts of Suicidal Ideations
- Increased Anhedonia
- Easily Developed Anxiety
The Benefits of SPRAVATO
For patients who qualify, esketamine treatments may offer distinct advantages as part of a comprehensive treatment plan. The approach and administration method differ from many standard oral medications. Here’s more on the benefits of SPRAVATO:
Faster Activation
Unlike many antidepressants that can take several weeks or even months to show their full effect, SPRAVATO works more rapidly on brain pathways associated with mood regulation. This is particularly significant for individuals experiencing severe depressive symptoms who have not had success with other treatments. With esketamine treatments, many patients find relief from their depressive symptoms within 24 hours.
Safe Administration
SPRAVATO is only administered in a certified medical facility under direct supervision. This controlled setting makes sure that the treatment is delivered correctly and allows for immediate observation by a healthcare professional. This structured approach provides a supportive and monitored environment for the patient during and after each administration session.
Schedule an Appointment Today
Understanding your treatment options for severe or treatment-resistant depression necessitates a conversation with a qualified medical professional. A healthcare provider can assess your medical history, discuss your symptoms, and help you create a personalized care plan. If you have questions about esketamine treatments, contact a specialist for a consultation today.
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